4In 2007, Barrangou et al. demonstrated for the first time the function of CRISPR/Cas9 as a defensive mechanism of bacteria against bacteriophage attacks by a technique called “plaquing” which builds upon the technique of “plating” bacteria on agar. Plaques of viruses on agar are areas without growth of bacteria due to viral attacks.
def _init_table(self) - None:
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Randomly selecting border points or using simple geometric divisions (squares/hexagons) results in too many border points per cluster (50-80). This leads to a shortcut explosion (N*(N-1)/2 shortcuts), making the files large and and calculations slow.
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for (int gap = n / 2; gap 0; gap /= 2) {